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"Cell" is not inferior to the previous two books in terms of reputation.

The reason why few people know it is because this top scientific magazine is limited to one field-life science research.

Compared with comprehensive scientific magazines, Cell's popularity or audience will definitely be much smaller.

But if we look solely at the academic achievements of this journal, it is definitely the best in the world.

It can be said that the world-renowned life science research results are published in this magazine.

Cell’s global impact factor is as high as 31.027.

This index is also among the best in the world.

So much so that in the selection of the Nobel Prize, whether a paper published by a certain scientist can be selected for Cell is also a very important consideration.

What Angel is most interested in is one of the research reports jointly released by four research institutions, titled "Revealing How Tissues Protect DNA from Damage Under Mechanical Pressure."

In daily life, the body's tissues, such as skin and muscles, are stretched, stretched and compressed without causing damage to cells or DNA.

A team of researchers led by Sara Wi from the Max Planck Institute, the Institute for the Biology of Aging, the CECAD Group of Excellence at the University of Cologne and the Institute of Life Sciences at the University of Helsinki have discovered the mechanisms by which cells protect themselves against these stresses, including in the nucleus

Deforming and softening the genetic material itself.

To study how DNA in stem cells responds to mechanical deformation, the researchers used a special mechanical device to expose skin and muscle stem cells to mechanical stretch conditions similar to those they experience within tissues.

As a result of stretching, both the cell nucleus and DNA are reorganized, which also changes their mechanical properties and makes them softer.

This suggests that the mechanical properties of DNA can be changed by applying mechanical force to stem cells, an exciting finding.

Even more strikingly, if this change is experimentally prevented, the stem cells are now exposed to DNA damage, suggesting that humans have discovered an important protective mechanism.

While delving into the cellular mechanisms of stem cells' response to stretch, Nava, Miroshnikova and colleagues found that if exposed to mechanical stretch for longer periods of time, the entire tissue moves in the direction of the force.

This tissue-scale positioning prevents the nucleus and its DNA from deforming, returning them to their original state.

This tissue-level orientation thus serves as long-term mechanical protection.

Finally, the researchers also noticed that cancer cells are less sensitive to mechanical stretch than healthy stem cells due to differences in the levels of key nuclear proteins.

Conventionally, two core features that define cancers are their genetic instability, that is, the frequent acquisition of new mutations, and their insensitivity to control by external signals.

A major future goal for the four institutions is to understand how defects in this newly discovered pathway promote cancer formation, and how cancer exploits these mechanisms to escape the tissue's control mechanisms.

"It's interesting. If we continue on the current research path, we may be able to touch the threshold of super skin in another 800 years." After reading the magazine, Angel gently closed it and placed it on the coffee table aside.

Ding dong, ding dong, ding dong~

Angel had just put down the magazine in his hand when the doorbell rang.

She glanced towards the door but did not get up.

Without looking, she knew who was outside the door and knew his purpose.

I specially picked something to eat here, and it’s all about eating!

Li Yueli's cooking skills have improved a lot during this period, and the dishes she cooks are getting more delicious every day.

After all, with a monthly salary of more than 100,000 yuan, she would be too embarrassed to hang around here.

Angel worked during the day. After cleaning the house, she started thinking about cooking and even signed up for a training class by a well-known domestic chef.

Hard work pays off, and now Li Yueling's cooking skills are definitely qualified to work as a chef in a starry restaurant.

After Wu Jun tasted Li Yueling's cooking twice, he came to Angel's house every now and then to have a meal, and he didn't regard himself as an outsider at all.

"Mr. Wu must be here. I'll open the door." Li Yueli wiped her hands and came out of the kitchen to open the door.

As soon as I opened the door, sure enough, Wu Jun was standing outside the door carrying a bag of ingredients.

Li Yueling took the ingredients from Wu Jun's hand and carried them to the kitchen to clean them up.

When Wu Jun came to Angel's house, he didn't regard himself as an outsider at all.

After putting on slippers at the door, he walked to sit opposite Angel.

Seeing the magazine that Angel left on the table, Wu Jun picked it up curiously and flipped through a few pages.

After flipping through a few pages, he found that they were all in English.

He does recognize all 26 English letters, but when these English letters are arranged in a certain order, he doesn't recognize them very well.

Wu Jun put the magazine back to its original position with a slightly embarrassed expression.

Angel crossed her arms and looked at Wu Jun, with a smile on her face: "If you are interested, can I translate it for you on the spot?"

"Forget it, I'm just a little curious. If I don't understand it, I won't read it. Anyway, I won't lose anything."

Wu Jun waved his hand, changed the subject and asked: "By the way, Angel, how is the progress at Runzhong Real Estate? When will I start cooperating with you?"

In order to cooperate with Angel in arranging Gao Jianxiong, Wu Jun used all his connections in Pingshan.

They even found County Magistrate Qiao Yiwei, and the case of Zhao Hui and others' attempt to create chaos at the party was suppressed until now.

More than half a month has passed since the day of the incident.

Wu Jun felt a little embarrassed for having troubled Qiao Yiwei for so long.

Angel looked like she was sure of winning, and said slowly: "Runzhong Real Estate's stock has been raised to the point, and we can proceed as planned next Monday."

After Wu Jun received Angel's assurance, he felt much lighter.

"How much money do you expect to make this time?" What Wu Jun is most interested in is this.

Originally, he was not too interested in making money, but he still wanted to discuss the matter.

He is still very interested in making money from Gao Jianxiong.
Chapter completed!