282 Artemisinin Extraction
Unlike Bronia's worry, Fu Song is happily collecting Artemisia annua all over the world.
But he was stunned very soon.
Because in just half an hour, Fu Song found 17 Artemisia species.
As for which type of Artemisia annua extracted from Grandma Tu, uh...the leaves are all green anyway.
This cannot be blamed on Fu Song. There are more than 300 species of artemisia in the world.
In addition, the leaves of Artemisia are almost the same, so it is impossible for professionals to tell them.
Finally, Fu Song picked all the artemisiae back.
At worst, it’s harder to analyze it.
In fact, all artemisinin is found in all artemisinin, but the content is different. Fu Song only needs to find the one with the highest purity.
He started to do experiments.
However...how to do it?
Fu Song was stunned again.
His only experimental experience was his cooperation with Dou Hongyi in the laboratory of Hua Agricultural University.
As an assistant, Fu Song played the finishing touch in the experiment.
At that time, he thought it was easy, but now he found that it was not as simple as he thought.
But experimental design is enough to drive him crazy.
Holding a thick book of information, Fu Song muttered: "It would be great if Dou Hongyi was there. That guy usually looks careless, but he really has a good way of doing experimental design."
Next to him, Zhang Jiuyue, who had been busy with Fu Song, smiled: "You can't call Dou Hongyi over.
As the saying goes, "Across the roads are like mountains". The other party is an expert in agriculture, but your experiments are related to medicine.
There is no match for both."
Fu Song: "What should I do? I can't come back first for a doctorate in medicine for an experiment, right?"
Zhang Jiuyue said helplessly: "I said you are so smart, why did you suddenly become stupid at the critical moment?
Isn’t there a ready-made doctor of medicine here?”
Fu Song: "You mean Simon?"
"And Bronia!"
Bang!
Fu Song slapped the face and said, "I'm really stupid."
Simon was called over by Fu Song: "Advisor, ask you a question, can you extract the pharmaceutical ingredients in plants?"
Simon was stunned: "What did you say?"
Seeing that Simon didn't seem to understand, Fu Song was a little disappointed: "No, then forget it."
He did not question it. After all, he specialized in his profession, so it was indeed a bit embarrassing to let an expert in surgery study drug analysis.
As a result, I heard Simon say: "The thing about extracting pharmacy from plants is just a basic job I did when I was in my freshman year.
I didn't touch this kind of cool work without any technical content ten years ago, and now I'm giving it all to my students."
Fu Song: "..."
OK, before I knew it, I was actually loaded by this guy.
"Then can you do it now?"
Simon: "If a high school student is asked to calculate addition and subtraction within ten, do you think he can calculate 100% correct?"
Fu Song: "..."
You can't speak well, right?
He said directly: "Now I'll give you a task. Have you seen these artemisiae? You can find a way to separate their chemical components, and the thinner the better.
Remember, when separation, remember to do it under low temperatures.”
Artemisinin is easy to decompose at high temperatures. Once the temperature exceeds 80 ℃, all efforts will be ruined.
Fu Songben thought he was not clear enough, so he was about to add a few more words, so he heard Simon say, "No problem, I guarantee to complete the task."
He quickly listed a table, and then used a method to dazzle Fu Song to separate the rhizomes of all the artemisia he picked.
Crush, filter, evaporate, dissolve, extract...
Simon's hands were like magic, and it took only half a day to make hundreds of samples.
Fu Song couldn't help but give him a thumbs up: "I am a top student in the Department of Medicine at Harvard University, awesome!"
Simon pointed to the simple experimental equipment in front of him: "Please don't insult my university, thank you!"
Fu Song: "..."
However, he no longer cared about talking nonsense with the other party, because lines of red fonts appeared in Fu Song's eyes.
That’s right, this is also one of Fu Song’s confidence in extracting artemisinin on the spot.
If you want to accurately analyze the ingredients of a certain drug according to the general situation, you need very precise instruments.
This is simply impossible to do with a tribe with poor facilities in Africa.
But it’s different with your own eyes.
As long as these artemisiae are separated into roughly, Fu Song can determine which artemisinin content has a higher content.
Soon, Fu Song took out the experimental group No. 67 and asked Simon: "What kind of artemisia arising from it?"
Simon said: "Big Leaf Artemisia saccharomycea."
Fu Song nodded: "It's it."
He finally breathed a sigh of relief.
Many people subconsciously believe that Grandma Tu won the award for artemisinin, so the best-effect artemisinin must be extracted from the purest Artemisinin.
In fact, the artemisinin extracted from Artemisia annua is only effective for malaria vivax and has little effect on malaria falciparum.
The artemisinin extracted from Artemisia agaricus is not only effective for malaria vivax, but also effective for malaria falciparum.
However, Grandma Tu first discovered artemisinin, and flavinin was discovered secondary based on the discovery of artemisinin, and its reputation was not as great as artemisinin.
He found Chief Dies and asked him to gather his tribe members to pick Artemisia anthracite.
"Dies, I won't let everyone be in vain. I will buy all the wormwood they picked back."
Unexpectedly, Dies shook his head: "Dear Fu, I know what you are doing.
So please rest assured that my tribe members are very happy to serve, free of charge.”
"That's so thankful." Fu Song did not refuse, and turned around and discussed the purification plan with Simon.
The extraction solvent for flavinin is divided into two types: diethyl ether and alcohol. Fu Song chooses the easy-to-get alcohol.
When he was ready, Dies happened to come back with his tribe members holding a large number of large-leaf wormwood.
Another busy work, Fu Song took out a beaker with half a cup of liquid inside.
Putting the beaker in front of Bronia, Fu Song clapped his hands and said, "Get the new medicine you want, get it done."
Bronia looked at him suspiciously: "What new drug?"
"Of course it's a new drug for treating malaria!"
Bronia opened her mouth in surprise: "So fast?"
It’s not that she doesn’t believe in Fu Song, but that it’s only been one day since she put forward the conditions.
The development of a new drug can take several months even if it is fast. It would be great if you can formulate a general plan in one day.
Fu Song laughed: "It's a special matter. Time is money. One day, you will lose millions more. I won't be careless."
Seeing that Bronia was still in a daze, Fu Song said again: "Do you doubt the effect of this thing?
Didn’t those who were all patients before? You’ll know if you’re trying it out.”
Bronia came to her senses and she quickly stood up and rushed towards the quarantine area.
Chapter completed!